method for treatment of generalized periodontitis on the background of system antibiotic therapy of accompanied pathology

• 1. 一种广义高斯纹理海杂波背景下的目标检测方法及装置 [P] . 中国专利： CN113009444A . 2021-06-22
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• 3. METHOD FOR SYSTEMIC ANTIBIOTIC THERAPY IN NON-SURGICAL TREATMENT OF CHRONIC GENERALIZED PERIODONTITIS [P] . UA88041U . 2014-02-25

  机译： 慢性牙周炎非手术治疗的系统性抗生素治疗方法

• 4. METHOD FOR ORAL CAVITY DYSBIOSIS TREATMENT IN PATIENTS WITH GENERALIZED PARADONTOSIS AGAINST SYSTEMIC ANTIBIOTIC THERAPY OF CONCOMITANT PATHOLOGY [P] . UA66715U . 2012-01-10

  机译： 全身性抗寄生虫病伴随病理学治疗全身性泛滥的口腔龋齿症

• 5. METHOD FOR COMPLEX TREATMENT OF GENERALIZED PERIODONTITIS BY PHOTODYNAMOTHERAPY [P] . UA77137U . 2013-01-25

  机译： 光动力疗法综合治疗广义牙周病的方法

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• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. Comparison of dental pulp periodontal therapy and conventional simple periodontal therapy as treatment modalities for severe periodontitis [J] . Lu Li ,Hong-Jie Chen ,Yi Lian . 世界临床病例杂志 . 2021,第033期
• 3. A Practical Method to Evaluate and Verify Dose Calculation Algorithms in the Treatment Planning System of Radiation Therapy [J] . Lanchun Lu ,Guy Yembi-Goma ,Jian Z. Wang . 医学物理学、临床工程、放射肿瘤学（英文） . 2013,第3期
• 4. Generalized periodontitis treated with periodontal,orthodontic,and prosthodontic therapy:A case report [J] . Masato Kaku ,Shinji Matsuda ,Takayasu Kubo . 世界临床病例杂志 . 2021,第021期
• 5. Generalized Attack Model for Networked Control Systems, Evaluation of Control Methods [J] . Arman Sargolzaei ,Kang Yen ,Mohamed Abdelghani . 智能控制与自动化（英文） . 2017,第3期
• 6. 眼附属器黏膜相关淋巴组织淋巴瘤伴浆细胞样分化和T细胞背景病理学特征分析 [C] . 马小梅 . 上海市病理专科分会2010年年会 . 2010
• 7. C反应蛋白指导下的新生儿疑诊早发型败血症抗生素治疗策略 [A] . 何云雁 . 2020