• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Antimicrobial photodynamic therapy compared to systemic antibiotic therapy in non-surgical treatment of periodontitis: Systematic review and meta-analysis
【24h】

Antimicrobial photodynamic therapy compared to systemic antibiotic therapy in non-surgical treatment of periodontitis: Systematic review and meta-analysis

机译：抗菌光动力治疗与牙周炎非手术治疗中的全身抗生素治疗相比：系统审查和荟萃分析

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Periodontitis is one of the most prevalent inflammatory diseases in humans. It is associated with the presence of bacteria and is mediated by the hosts immune response This study represents a systematic review and meta-analysis trying to answer the following question: "What is the effect of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) compared to systemic antibiotic therapy with amoxicillin plus metronidazole (AMX + MTZ) on the non-surgical treatment of periodontitis?".Methods: Clinical studies comparing aPDT with systemic use of AMX + MTZ were searched until January of 2020 using the databases: PubMed, MEDLINE, SCOPUS, EMBASE, Cochrane Central, Web of Science and Scielo, as well manual searches in related journals. Periodontal clinical parameters such as probing depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP) were statistically analyzed.Results: Five randomized clinical studies (RCTs) were included within the eligibility criteria, and served as a basis for qualitative and quantitative analyzes. All the studies reported an improvement in the clinical parameters with both therapies, although in a direct comparison, our analyzes did not find statistical differences that indicate the superiority of one supporting treatment in relation to the other.Conclusion: Although the limited number of RCTs and the great heterogeneity between them, it can be concluded that aPDT presents similar clinical results compared to antibiotic therapy with AMX + MTZ as adjuvants in the non-surgical treatment of periodontitis.
机译：背景：牙周炎是人类最普遍的炎症性疾病之一。它与细菌的存在有关，并且由宿主免疫反应介导该研究该研究代表了一个系统的审查和荟萃分析，试图回答以下问题：“抗菌光动力治疗（APDT）的效果是什么样的缩放和根刨（SRP）与Sysic抗生素治疗与Amoxicillin Plus甲硝唑（AMX + MTZ）的非手术治疗进行了牙周炎的非手术治疗相比？“。方法：搜查了APDT与APDT的APDT的临床研究，截至2020年1月使用数据库：PUBMED，MEDLINE，SCOPUS，EMBASE，Cochrane Central，Science和Scielo Web，以及手动搜索相关期刊。衰退（Pd），临床附着水平（Cal）和探测（BOP）出血的牙周临床参数在统计学上进行了统计学分析。结果：五项随机临床研究（RCT）包括在资格标准中，并作为基础定性和定量分析。所有研究报告说，临床参数与两种疗法有所改善，虽然在直接比较中，我们的分析并没有找到统计差异，表明与另一个相关的一个支持处理的优势。结论：虽然RCT数量有限它们之间的巨大异质性，可以得出结论，与AMX + MTZ的抗生素治疗相比，APDT与AMX + MTZ的抗生素治疗相比，APDT呈现出类似的临床疗法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号