首页>
外国专利>
Expression systems using mammalian beta-actin promoter
Expression systems using mammalian beta-actin promoter
展开▼
机译:使用哺乳动物β-肌动蛋白启动子的表达系统
展开▼
页面导航
摘要
著录项
相似文献
摘要
Promoter activities were examined by comparing combinations of promoters and enhancers derived from various genes. A hybrid promoter comprising a combination of a CMV enhancer and a mammalian β-actin promoter, or the post-transcriptional regulatory region of the genomic sequence Woodchuck Hepatitis Virus (WPRE) and a mammalian β-actin promoter was found to be stronger than existing promoters. Furthermore, the activities of the β-actin promoters could be enhanced by coexpressing the oncogene product Ras, which is a transactivator.
展开▼