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High Fluorescence Quantum Yield Hydrophobic Fluorescent Probe, Biopolymer Detection Method Using It, and Interaction Detection Method between Biopolymers
High Fluorescence Quantum Yield Hydrophobic Fluorescent Probe, Biopolymer Detection Method Using It, and Interaction Detection Method between Biopolymers
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机译:高荧光量子产率疏水荧光探针,使用它的生物聚合物检测方法以及生物聚合物之间的相互作用检测方法
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摘要
[PROBLEMS] To provide a hydrophobic fluorescent probe molecule of the high-fluorescent quantum efficiency type which enables highly sensitive detection in vivo, a method of detecting a biopolymer and a method of detecting an interaction between biomolecules by using this hydrophobic fluorescent probe molecule of the high-fluorescent quantum efficiency type. [MEANS FOR SOLVING PROBLEMS] A fluorescent probe wherein an arylethynyl group having a substituent is introduced into a fluorescent organic group capable of forming an excimer which is typified by a fluorescent probe having an arylethynyl group substituted with a maleimide group introduced at the 1-position of a pyrene skeleton. A method of detecting a biopolymer and a method of detecting an interaction between biomolecules which can be carried out by labeling a test biopolymer with this fluorescent probe molecule.
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