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Antibacterial zinc oxide (ZnO) nanoparticles doped with copper or magnesium

机译:铜或镁​​掺杂的抗菌氧化锌(ZnO)纳米颗粒

摘要

A method for the manufacture of colloidal ZnO particles doped with Cu or Mg comprises the steps of (i) dissolving salts of Zn and Cu or Mg in an alcoholic solution, preferably methanol or ethanol, to form a reaction mixture (ii) heating, preferably to a temperature of 60 to 65°C, and stirring the reaction mixture until a clear solution is formed (iii) adding a basic solution, preferably KOH in methanol, at room temperature drop by drop with vigorous stirring and (iv) heating the reaction mixture, preferably for at least 22 hrs at 60 to 65°C. Preferably the precursor salts of Zn, Cu and Mg are selected from zinc acetate, copper acetate and magnesium nitrate. The ZnO nanoparticles doped with Cu or Mg may be spherical or rod shaped and may be further bound to a polymer. The antibacterial ZnO/Cu and/or ZnO/Mg particles may be used in pharmaceuticals, cosmetics, medicines, disinfectants, antibacterial coatings or in the manufacture of textiles or fibres.
机译:制造掺杂有Cu或Mg的胶体ZnO颗粒的方法包括以下步骤:(i)将Zn和Cu或Mg的盐溶解在醇溶液中,优选甲醇或乙醇,以形成反应混合物;(ii)加热,优选至60-65℃的温度,并搅拌反应混合物直至形成澄清溶液(iii)在室温下在剧烈搅拌下逐滴加入碱性溶液,优选在甲醇中的KOH,并且(iv)加热反应混合物,最好在60到65°C下至少搅拌22小时。优选地,Zn,Cu和Mg的前体盐选自乙酸锌,乙酸铜和硝酸镁。掺杂有Cu或Mg的ZnO纳米颗粒可以是球形或棒状的,并且可以进一步结合到聚合物上。抗菌ZnO / Cu和/或ZnO / Mg颗粒可用于药物,化妆品,药​​品,消毒剂,抗菌涂层或纺织品或纤维的生产中。

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