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Colorectal Cancer Diagnostic Markers Using Colorectal Cancer Overexpression Genes
Colorectal Cancer Diagnostic Markers Using Colorectal Cancer Overexpression Genes
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机译:大肠癌过表达基因的大肠癌诊断标记
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摘要
PURPOSE: A marker for diagnosisng colon cancer is provided to accurately diagnose colon cancer in early time and determined metastasis and prognosis of colon cancer. CONSTITUTION: A marker for specifically diagnosing colon cancer is MAD2L1MAD2 mitotic arrest deficient-like 1(yeast)(GenBank No. NM_002358), CCNB1cyclin B1(GenBank No. NM_031966) or CSEILCSE1 chromosome segregation 1-like(yeast)(GenBank No. NM_001316). A composition for diagnosing colon cancer contains an agent for measuring mRNA or its protein level of MAD2L1, CCNB1 or CSEIL gene. The agent for measuring the mRNA level is a primer which specifically binds to the gene. A method for providing information for colon cancer diagnosis comprises: a step of measuring mRNA from a biological sample of a patient which possibly has colon cancer; and a step of comparing mRNA level with control group mRNA level.
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