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RECOMBINANT G(-) BACTERIA WHICH PRODUCES TOXICITY-REMOVED OUTER MEMBRANE VESICLE AND A METHOD FOR PREPARING THE OUTER MEMBRANE VESICLE USING THE SAME
RECOMBINANT G(-) BACTERIA WHICH PRODUCES TOXICITY-REMOVED OUTER MEMBRANE VESICLE AND A METHOD FOR PREPARING THE OUTER MEMBRANE VESICLE USING THE SAME
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机译:产生毒性去除的外膜囊泡的重组G(-)细菌及使用该膜制备外膜囊泡的方法
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摘要
PURPOSE: A method for preparing toxicity-removed outer membrane vesicle using a recombinant G(-) bacteria is provided to be used as a bionano vaccine.;CONSTITUTION: A method for preparing outer membrane vesicle(OMV) in which toxicity is removed comprises: a step of culturing a recombinant G(-) bacteria and producing toxicity-removed OMV; and a step of collecting the secreted OMV. The recombinant G(-) bacteria is prepared by deleting a gene encoding toxic sit of exotoxin from G(-) bacteria which has exotoxin and OMV generation ability.;COPYRIGHT KIPO 2011
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