首页> 外国专利> TREATMENT OF PSYCHIATRIC PATIENTS WITH SLEEP DISORDERS AND / OR EXCESSIVE TAGESSLESSNESS WITH PALIPERIDONE

TREATMENT OF PSYCHIATRIC PATIENTS WITH SLEEP DISORDERS AND / OR EXCESSIVE TAGESSLESSNESS WITH PALIPERIDONE

机译:帕立哌酮治疗睡眠障碍和/或过度无症状的精神分裂症患者

摘要

The present invention provides a pharmaceutical composition, and provides for the use thereof for the treatment of excessive daytime sleepiness and/or a sleep disturbance in a psychiatric patient in need thereof. The pharmaceutical composition comprises a therapeutically effective amount of paliperidone, its pharmaceutically acceptable acid addition salts, enantiomeric forms, and esters thereof, together with a pharmaceutical carrier, and provides a relatively low plasma concentration variation of paliperidone to the psychiatric patient in need of treatment. The present invention also provides for the use of a pharmaceutical composition as defined above, in the preparation of a medicament for the treatment of excessive daytime sleepiness and/or a sleep disturbance in a psychiatric patient in need thereof.
机译:本发明提供了药物组合物,并提供了其在治疗需要其的精神病患者中过度的白天嗜睡和/或睡眠障碍的用途。该药物组合物包含治疗有效量的帕潘立酮,其药学上可接受的酸加成盐,对映体形式及其酯,以及药物载体,并且为需要治疗的精神病患者提供帕潘立酮的血浆浓度变化相对较低。本发明还提供了如上定义的药物组合物在制备用于治疗需要其的精神病患者中过度的日间嗜睡和/或睡眠障碍的药物中的用途。

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