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AGONIST OF GLUCOCORTICOID RECEPTOR, CONTAINING NEW DERIVATIVES OF 1,2,3,4-TETRAHYDROCHINOXALINE WITH A FENILE GROUP, HAVING A STRUCTURE OF SULPHONIC ACID ETHER, WEFAN, A HIGH VEHICLE, A HIGH VOLUME ACCELERATED TELEPHONIC ACID, A HIGH VOLUME ACCELERATED, HAVE A VOLVOUS AREA, A HIGH VOLUME ACCESS, A VOLUME ACCESS, A VOLUME ACCESS, A VOLUME ACCESS, A WOLFEROUS ACID, A VOLUME ACCESS, A TURN-HYDRAIC ACID;
AGONIST OF GLUCOCORTICOID RECEPTOR, CONTAINING NEW DERIVATIVES OF 1,2,3,4-TETRAHYDROCHINOXALINE WITH A FENILE GROUP, HAVING A STRUCTURE OF SULPHONIC ACID ETHER, WEFAN, A HIGH VEHICLE, A HIGH VOLUME ACCELERATED TELEPHONIC ACID, A HIGH VOLUME ACCELERATED, HAVE A VOLVOUS AREA, A HIGH VOLUME ACCESS, A VOLUME ACCESS, A VOLUME ACCESS, A VOLUME ACCESS, A WOLFEROUS ACID, A VOLUME ACCESS, A TURN-HYDRAIC ACID;
The aim of the invention is the search for a new pharmacological activity of a new derivative of 1,2,3,4-tetrahydroquinoxaline containing, as a substituent, a phenyl group having a sulfonic acid ester structure introduced therein. The compound represented by general formula (1) or a salt thereof is useful as a glucocorticoid receptor agonist, in particular as a therapeutic agent against diseases against which a glucocorticoid receptor agonist (e.g., a steroid) such as inflammatory bone-articular joints is believed to be effective. diseases, inflammatory eye diseases (inflammatory eye diseases of the anterior or posterior chamber of the eye). In the above formula, R represents a group represented by the general formula (2a), (3a), (4a) or (5a); R represents a lower alkyl group which may have a substituent, a lower cycloalkyl group which may have a substituent, or a similar group; R represents a lower alkyl group; R, R, R or R represents a halogen atom, a lower alkyl group which may have a substituent, a hydroxyl group, a lower alkoxy group which may have a substituent, or a similar group; and m, n, p or q is 1 or 2.
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