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Being the manner which decides the transplantation aptitude decision manner, and quality control manner of culture cartilage system and the transplantation aptitude of production mannered null
Being the manner which decides the transplantation aptitude decision manner, and quality control manner of culture cartilage system and the transplantation aptitude of production mannered null
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机译:作为决定移植能力决定方式的方式,培养软骨体系的质量控制方式和生产移植能力的决定方式无效。
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摘要
PROBLEM TO BE SOLVED: To objectively and efficiently decide suitability for transplantation of a cultured tissue and to efficiently supply the cultured tissue having a stable quality by an objective criterion. SOLUTION: A pH value of 6.9 corresponding to 1×106 cultured cartilage cells/ml is set to a criterial pH value in a cultured cartilaginous tissue. The decision that the cultured cartilaginous tissue has suitability for transplantation is drawn when the pH value measured after starting culturing is less than 6.9 because the number of the cells and the production amount of a substrate increase and the pH value decreases accompanied with a lapse of a culture period in the cultured cartilaginous tissue. The quality is controlled by regulating the culture period, or the like, based on the comparison with the criterial pH value.
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