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BRAIN DISEASE PROGRESSION SCORING METHOD AND APPARATUS

机译：脑病进展评分方法和装置

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摘要

A method of characterising the state of brain disease within a candidate subject, the method comprising the steps of: (a) acquiring brain data of the brain of a number of subjects, each of the subjects having a known brain state or condition relative to the brain disease; (b) utilising a dimensionality reduction statistical method on the brain data to form a series of component vectors, (c) collecting like brain data states to determine a healthy brain cluster position in the principal component space and a brain disease condition cluster position in the principal component space; (d) for the candidate subject, acquiring the physiological brain data for the candidate subject, and, mapping the candidate subject's brain data to the components vectors; (e) determining a relative position of the mapping of the candidate subject's brain data relative to the healthy cluster position and the brain condition cluster position; and utilising the relative position as a measure of characterisation of the state of brain disease within the candidate subject.

机译：一种表征候选受试者内脑疾病状态的方法，该方法包括以下步骤：（a）获取多个受试者的大脑的大脑数据，每个受试者相对于该受试者具有已知的大脑状态或状况。脑疾病（b）对大脑数据使用降维统计方法以形成一系列成分向量，（c）收集类似大脑数据的状态，以确定主成分空间中健康的大脑簇位置以及大脑中疾病状况簇的位置主成分空间; （d）对于所述候选对象，获取所述候选对象的生理脑数据，并将所述候选对象的脑数据映射到所述分量矢量; （e）确定候选受试者的大脑数据相对于健康簇位置和脑部状况簇位置的映射的相对位置;并利用相对位置作为候选对象内脑疾病状态表征的量度。

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公开/公告号WO2010085856A1

专利类型
公开/公告日2010-08-05

原文格式PDF
申请/专利权人 COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION;FRIPP JURGEN;SALVADO OLIVIER;BOURGEAT PIERRICK;
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申请/专利号WO2010AU00095
发明设计人 BOURGEAT PIERRICK;FRIPP JURGEN;SALVADO OLIVIER;
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申请日2010-02-02
分类号A61B5/055;G06T7/00;
国家 WO
入库时间 2022-08-21 18:36:53

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