首页> 外国专利> GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUT COME PREDICTION IN PEDEATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

GENE EXPRESSION CLASSIFIERS FOR RELAPSE FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE IMPROVE RISK CLASSIFICATION AND OUT COME PREDICTION IN PEDEATRIC B-PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA

机译：用于缓解游离生存和最小残留病的基因表达分类器可改善儿童B型前列腺癌急性淋巴白血病的风险分类和预后预测

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摘要

The present invention relates to the identification of genetic markers patients with leukemia, especially including acute lymphoblastic leukemia (ALL) at high risk for relapse, especially high risk B-precursor acute lymphoblastic leukemia (B-ALL) and associated methods and their relationship to therapeutic outcome. The present invention also relates to diagnostic, prognostic and related methods using these genetic markers, as well as kits which provide microchips and/or immunoreagents for performing analysis on leukemia patients.

机译：本发明涉及具有高复发风险，特别是高风险B前体急性淋巴细胞白血病（B-ALL）的白血病，尤其包括急性淋巴细胞白血病（ALL）的遗传标志物的鉴定及其相关方法及其与治疗的关系结果。本发明还涉及使用这些遗传标记的诊断，预后和相关方法，以及提供用于对白血病患者进行分析的微芯片和/或免疫试剂的试剂盒。

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公开/公告号WO2010056351A2

专利类型
公开/公告日2010-05-20

原文格式PDF
申请/专利权人 STC.UNM;WILLMAN CHERYL L.;HARVEY RICHARD;KANG HUINING;BEDRICK EDWARD;WANG XUEFEI;ATLAS SUSAN;CHEN I-MING;
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申请/专利号WO2009US06117
发明设计人 HARVEY RICHARD;KANG HUINING;ATLAS SUSAN;WILLMAN CHERYL L.;BEDRICK EDWARD;WANG XUEFEI;CHEN I-MING;
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申请日2009-11-16
分类号C12Q1/68;C12N15/12;
国家 WO
入库时间 2022-08-21 18:38:05

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