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Methods for CpG receptor (CpG-R) and CpG-R

机译:CpG受体(CpG-R)和CpG-R的方法

摘要

The present invention is directed to nucleic acid molecules and polypeptides encoding a CpG receptor (CpG-R). The CpG-R contains a THD, interacts with the MyD88 adapter protein, and may bind to CpG oligonucleotides. The present invention is also directed to antibodies against CpG-R and to methods of modulating an immune response and to methods of identifying compounds which bind to and/or modulate CpG-R.
机译:本发明涉及编码CpG受体(CpG-R)的核酸分子和多肽。 CpG-R包含THD,可与MyD88衔接蛋白相互作用,并可与CpG寡核苷酸结合。本发明还涉及针对CpG-R的抗体和调节免疫应答的方法,以及鉴定结合和/或调节CpG-R的化合物的方法。

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