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Polynucleotides Sequence Associated with Apoptosis Induced from Cleavage of Caspase-7, Inhibitor or Inducer of the Apoptosis, and The Screening Method thereof
Polynucleotides Sequence Associated with Apoptosis Induced from Cleavage of Caspase-7, Inhibitor or Inducer of the Apoptosis, and The Screening Method thereof
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机译：Caspase-7裂解诱导的凋亡相关多核苷酸序列，凋亡抑制因子或诱导剂及其筛选方法
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摘要
A polynucleotide sequence associated with apoptosis induced from cleavage of caspase-7 is provided to develop the inducer of apoptosis useful for treating cancer, autoimmune disease, virus infection and endocrine system disease. The purified or isolated polynucleotide sequence associated with apoptosis induced from cleavage of caspase-7 comprises one selected from (a) the polynucleotide sequence of SEQ ID NO:1, (b) the polynucleotide sequence having more than 70% homology to the DNA of (a), (c) the polynucleotide sequence which hybridizes with the polynucleotide sequence of (a) or (b) under stringent condition, and (d) the polynucleotide sequence or RNA sequence complementary with the sequence of (a), (b) or (c).
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机译：提供了与由胱天蛋白酶7的切割诱导的凋亡相关的多核苷酸序列，以开发凋亡诱导剂，其可用于治疗癌症，自身免疫性疾病，病毒感染和内分泌系统疾病。与裂解caspase-7诱导的细胞凋亡相关的纯化或分离的多核苷酸序列包含一个选自（a）SEQ ID NO：1的多核苷酸序列，（b）与（c）DNA的同源性超过70％的多核苷酸序列（a），（c）在严格条件下与（a）或（b）的多核苷酸序列杂交的多核苷酸序列，和（d）与（a），（b）或（C）。
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