CRYSTAL STRUCTURES OF HIV-1 PROTEASE INHIBITORS BOUND TO HIV-1 PROTEASE

• 1. HIV-1病毒蛋白酶抑制剂耐药突变检测试剂盒及方法 [P] . 中国专利： CN103215348B . 2015.06.03
• 2. 含异山梨醇结构单元的HIV-1蛋白酶抑制剂及其制备方法与应用 [P] . 中国专利： CN102627654B . 2013.11.27
• 3. CRYSTAL STRUCTURES OF HIV-1 PROTEASE INHIBITORS BOUND TO HIV-1 PROTEASE [P] . 美国专利： US2010173381A1 . 2010-07-08

  机译： 与HIV-1蛋白酶结合的HIV-1蛋白酶抑制剂的晶体结构

• 4. CRYSTAL STRUCTURES OF HIV-1 PROTEASE INHIBITORS BOUND TO HIV-1 PROTEASE [P] . 欧洲知识产权局专利： EP2121589A2 . 2009-11-25

  机译： 与HIV-1蛋白酶结合的HIV-1蛋白酶抑制剂的晶体结构

• 5. CRYSTAL STRUCTURES OF HIV-1 PROTEASE INHIBITORS BOUND TO HIV-1 PROTEASE [P] . 世界知识产权组织专利： WO2008077070A2 . 2008-06-26

  机译： 与HIV-1蛋白酶结合的HIV-1蛋白酶抑制剂的晶体结构

• 1. Free energy calculation of single molecular interaction using Jarzynski's identity method: the case of HIV-1 protease inhibitor system [J] . De-Chang Li, Bao-Hua Ji 力学学报：英文版 . 2012,第003期
• 2. Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2'-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex. [J] . Oscarsson K, Lahmann M, Lindberg J, Bioorganic and medicinal chemistry . 2003,第6期
• 3. Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. [J] . Tyndall JD, Reid RC, Tyssen DP, Journal of Medicinal Chemistry . 2000,第19期
• 4. Bound Ligand Conformer Revealed by Flexible Structure Alignment in Absence of Crystal Structures: Indirect Drug Design Probed for HIV-1 Protease Inhibitors [J] . Alok Juneja, Henning Riedesel, Milan Hodoscek Journal of chemical theory and computation: JCTC . 2009,第3期
• 5. A Novel Sequence-Structure Approach for Accurate Prediction of Resistance to HIV-1 Protease Inhibitors [C] . Majid Masso, Iosif I. Vaisman IEEE International Symposium on Bioinformatics and Bioengineering . 2007
• 6. Crystallographic, molecular dynamics, and enzymatic studies of multi-drug resistant HIV-1 protease and implications for structure based drug design (project 1); crystallographic studies of human myelin protein zero (project 2). [D] . Liu, Zhigang. 2011
• 7. Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures. [O] . L Tong, S Pav, C Pargellis, 1993
• 8. Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures. [O] . Tong L, Pav S, Pargellis C, 1993

• 1. Exploring QSARs for Inhibitory Activity of Cyclic Urea and Nonpeptide-Cyclic Cyanoguanidine Derivatives HIV-1 Protease Inhibitors by Artificial Neural Network [J] . Omar Deeb ,Mohammad Jawabreh . 化学工程与科学期刊（英文） . 2012,第1期
• 2. Synthetic Studies of an Analogue of HIV-1 Protease Inhibitors of Didemnaketals:Construction of the C1-C8 Intermediate [J] . Ping Zhen WANG ,Yan Xing JIA ,Yong Qiang TU . 中国化学快报：英文版 . 1999,第9期
• 3. A new approach for HIV-1 protease cleavage site prediction combined with feature selection [J] . Yao Yuan ,Hui Liu ,Guangtao Qiu . 生物医学工程（英文） . 2013,第12期
• 4. Monitoring the autoproteolysis of hiv-1 protease by site-directed spin-labeling and electron paramagnetic resonance spectroscopy [J] . Jamie L. Kear ,Luis Galiano ,Angelo M. Veloro . 生物物理化学（英文） . 2011,第2期
• 5. 中国未接受蛋白酶抑制剂HIV-1感染者蛋白酶基因的多态性及耐药相关性变异 [C] . 刘莉 ,卢洪洲 ,Mireille Henry . 第五届中美临床微生物年会暨艾滋病机会感染研讨会 . 2009
• 6. HIV-1蛋白酶抑制剂解离速率常数的定量预测及解离机理研究 [A] . 屈素君 . 2017