首页> 外国专利> 3' - {N' - 1 - (3,4 - DIMETHYLPHENYL) - 3 - METHYL - 5 - OXO - 1,5 - DIHYDROPYRAZOL - 4 - YLIDENE HYDRAZINE} - 2' - HYDROXY - BIPHENYL - 3 - CARBOXYLIC ACID, 3' - {N' -1- (3,4 - DIMETHYLPHENYL) - 3 - METHYL - 5 - OXO - 1,5 - DIHYDROPYRAZOL - 4 - YLIDENE HYDRAZINE} - 2' - HYDROXY - 3' - (TETRAZOL - 5 - YL) - BIPHENYL COMPOUNDS AND THEIR DERIVATIVES AND THEIR USE IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HEMATOPOIETIC DISORDERS

3' - {N' - 1 - (3,4 - DIMETHYLPHENYL) - 3 - METHYL - 5 - OXO - 1,5 - DIHYDROPYRAZOL - 4 - YLIDENE HYDRAZINE} - 2' - HYDROXY - BIPHENYL - 3 - CARBOXYLIC ACID, 3' - {N' -1- (3,4 - DIMETHYLPHENYL) - 3 - METHYL - 5 - OXO - 1,5 - DIHYDROPYRAZOL - 4 - YLIDENE HYDRAZINE} - 2' - HYDROXY - 3' - (TETRAZOL - 5 - YL) - BIPHENYL COMPOUNDS AND THEIR DERIVATIVES AND THEIR USE IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HEMATOPOIETIC DISORDERS

机译：3'-{N'-[1-（3,4-二甲基苯基）-3-甲基-5-氧代-1,5-二氢吡唑-4-炔基] H]-2'-羟基-联苯-3-羧酸，3'-{N'-[1-（3,4-二甲基苯基）-3-甲基-5-氧代-1,5-二氢吡唑-4-炔基]肼}-2'-羟基-3'-（四唑-5-YL）-联苯酚化合物及其衍生物及其在制备治疗造血障碍的药物组合物中的用途

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摘要

3- { N'- [1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1 ,5-dihydropyrazol-4-ylidene]hydrazino }-2-hydroxy-3'-(tctrazol-5-yl)biphcnyl is useful as a TPO mimetic

机译：3- {N'-[1-（3,4-二甲基苯基）-3-甲基-5-氧代-1,5-二氢吡唑-4-亚烷基]肼基} -2-羟基-3'-（曲他唑-5- yl）biphcnyl可用作TPO模拟物

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公开/公告号IL152988A

专利类型
公开/公告日2009-02-11

原文格式PDF
申请/专利权人 SMITHKLINE BEECHAM CORPORATION;GLAXO GROUP LIMITED;SMITHKLINE BEECHAM CORPORATION;
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申请/专利号IL20020152988
发明设计人
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申请日2002-11-20
分类号C07D231/46;A61K;A61K31/41;A61K31/4152;A61K31/4155;A61K31/427;A61K31/435;A61K31/4439;A61K31/455;A61K31/675;A61K38;A61K39;A61K45;A61P7;A61P7/04;A61P37/04;A61P43;C07C205/59;C07C229/64;C07C309/49;C07C311/02;C07D213/79;C07D213/80;C07D231/48;C07D257/04;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D403/14;C07D405/04;C07D405/14;C07D409/04;C07D417/04;C07D417/12;
国家 IL
入库时间 2022-08-21 19:27:48

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