首页> 外国专利> Method for preventing skin-cellular injury by using green algae extract and cosmetic composition containing green algae extract

Method for preventing skin-cellular injury by using green algae extract and cosmetic composition containing green algae extract

机译:通过使用绿藻提取物防止皮肤细胞损伤的方法和含有绿藻提取物的化妆品组合物

摘要

A method for preventing UV-induced skin-cellular injury by using a green algae extract and a cosmetic composition containing the green algae extract are disclosed. An effective dose of the green algae extract is used to protect fibroblasts from UV-induced apoptosis. The mechanism of the disclosed method is using the green algae extract to inhibit interaction between apoptosis pathway molecules Fas/FasL so as to inhibit an adapter protein (FADD) in a death-inducing signaling complex (DISC) and in turn to inhibit caspase-3 activation and cleaved polymerase (PARP) such that irreparable damage to DNA can be prevented. The green algae extract can be mixed with a skin permeable cosmetic composition so that the cosmetic composition possesses the function of preventing skin from UV-induced injury.
机译:公开了一种通过使用绿藻提取物防止紫外线引起的皮肤细胞损伤的方法和包含该绿藻提取物的化妆品组合物。有效剂量的绿藻提取物用于保护成纤维细胞免受紫外线诱导的细胞凋亡。所公开方法的机理是使用绿藻提取物抑制凋亡途径分子Fas / FasL之间的相互作用,从而抑制诱导死亡的信号复合物(DISC)中的衔接蛋白(FADD),进而抑制caspase-3。激活和裂解的聚合酶(PARP),从而可以防止对DNA造成不可修复的损害。可以将绿藻提取物与皮肤可渗透的化妆品组合物混合,使得该化妆品组合物具有防止皮肤受到紫外线引起的伤害的功能。

著录项

  • 公开/公告号US2009142369A1

    专利类型

  • 公开/公告日2009-06-04

    原文格式PDF

  • 申请/专利权人 MENG-HAN SHIH;MEI-FEN SHIH;

    申请/专利号US20070998499

  • 发明设计人 MENG-HAN SHIH;MEI-FEN SHIH;

    申请日2007-11-30

  • 分类号A61K36/02;C12N9/99;

  • 国家 US

  • 入库时间 2022-08-21 19:31:59

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