首页>
外国专利>
PROCEDURE FOR MANUFACTURE OF SYNTHETIC OXYGEN VEHICLES FROM COVALENTLY RETICULATED HEMOGLOBINS WITH FUNCTIONAL PROPERTIES IMPROVED BY RETICULATION IN THE PRESENCE OF EFFECTS THAT DO NOT CHEMICALLY REACT THE OXYGEN BODY AFFINITY.
PROCEDURE FOR MANUFACTURE OF SYNTHETIC OXYGEN VEHICLES FROM COVALENTLY RETICULATED HEMOGLOBINS WITH FUNCTIONAL PROPERTIES IMPROVED BY RETICULATION IN THE PRESENCE OF EFFECTS THAT DO NOT CHEMICALLY REACT THE OXYGEN BODY AFFINITY.
展开▼
机译:在没有化学反应氧亲和力的情况下,通过网化改善功能功能的均价网状血球制造合成氧车辆的方法。
展开▼
页面导航
摘要
著录项
相似文献
摘要
A process for the production of synthetic oxygen vehicles by means of a bifunctional protein crosslinking agent, selected from butadiene diepoxide, divinylsulfone, a diisocyanate, especially hexamethylene diisocyanate, cyclohexyl diisocyanate and 2,5-bisisocyanatobenzenesulfonic acid, a di- N-hydroxysuccinimidyl ester, a diimidoester, or a dialdehyde, especially glyoxal, the glycoaldehyde that reacts analogously; or hemoglobin chemically crosslinked with glutardialdehyde with improved functional properties, characterized in that prior to covalent crosslinking of hemoglobin, effectors are added that do not chemically react from the oxygen affinity of hemoglobin selected from 2,3-bisphosphoglycerate, inositol hexaphosphate, Inositol hexasulfate or melitic acid at its reaction solution.
展开▼