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Method for Predicting if a patient is not responding to treatment with an agent specific Binding to a polypeptide of EGFR, which includes determining the presence or absence of a mutationK-ras and b-raf in a patient's tumor.
Method for Predicting if a patient is not responding to treatment with an agent specific Binding to a polypeptide of EGFR, which includes determining the presence or absence of a mutationK-ras and b-raf in a patient's tumor.
The present application relates to K-ras mutations, to polynucleotides encoding mutant K-ras polypeptides, and to methods of identifying K-ras mutations. The present application also relates to B-raf mutations, to polynucleotides encoding mutant B-raf polypeptides, to vectors containing those polynucleotides, and to methods of identifying B-raf mutations. The present application also relates to methods of diagnosing cancer; and methods and kits for predicting the usefulness of anti-EGFr specific binding agents in the treatment of tumors.
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