首页> 外国专利> use of polyunsaturated fatty acid or pharmacologically acceptable salt or salt thereof, method of topically treating conditions involving acutely or chronically inadequate immune response, oral dosage form, and pharmaceutical product

use of polyunsaturated fatty acid or pharmacologically acceptable salt or salt thereof, method of topically treating conditions involving acutely or chronically inadequate immune response, oral dosage form, and pharmaceutical product

机译:多不饱和脂肪酸或其药学上可接受的盐或盐的用途,局部治疗涉及急性或慢性免疫应答不足的病症的方法,口服剂型和药物产品

摘要

Use of Polyunsaturated Fatty Acid or a Pharmacologically Acceptable or Derived Salt of the Same, Topical Treatment Method of Chronic Inflammatory Conditions, and, Pharmaceutical Acid Fatty Acid or (or even) a Pharmaceutically Acid-Either ("PURPLE") (or DHA) is used in combination with at least one of an immunosuppressive agent or an antineoplastic agent or a pharmacologically acceptable salt or derivative thereof in the treatment of conditions involving acutely or chronically inadequate immune response by topically applying said active agents to at least one. part of the intestinal mucosa. Specific conditions that may be treated include chronic inflammatory disease (e.g. Crohn's disease and ulcerative colitis) and tumor-induced disease (e.g. bowel cancer and prostate cancer). An advantage of the preferred embodiments of the invention is that the bioavailability of immunosuppressive or antineoplastic agents is increased.
机译:多不饱和脂肪酸或其药理学上可接受或衍生的盐的使用,慢性炎性疾病的局部治疗方法以及药物酸性脂肪酸或(或什至)药物酸性任一种(“紫色”)(或DHA)的使用与免疫抑制剂,抗肿瘤药或它们的药理学上可接受的盐或衍生物中的至少一种组合使用,用于通过将所述活性剂局部施用于至少一种来治疗涉及急性或慢性免疫应答不足的疾病。肠粘膜的一部分。可以治疗的特定病症包括慢性炎性疾病(例如克罗恩氏病和溃疡性结肠炎)和肿瘤引起的疾病(例如肠癌和前列腺癌)。本发明优选实施方案的一个优点是提高了免疫抑制剂或抗肿瘤药的生物利用度。

著录项

  • 公开/公告号BRPI0511176A

    专利类型

  • 公开/公告日2007-12-04

    原文格式PDF

  • 申请/专利权人 TILLOTTS PHARMA AG;

    申请/专利号BR2005PI11176

  • 发明设计人 ULRICH MITTMANN;JEAN-PIERRE SACHETTO;

    申请日2005-06-15

  • 分类号A61K31/202;A61K9/48;A61K45/06;

  • 国家 BR

  • 入库时间 2022-08-21 20:08:47

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