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Conjugates with enhanced cellular uptake activity
Conjugates with enhanced cellular uptake activity
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机译:与增强的细胞摄取活性结合
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摘要
This invention relates to a conjugate molecule comprising at least one first portion (I) comprising a carrier sequence and at least one second portion (II) comprising at lest one anti-tumot drug molecule or a protease inhibitor molecule, said conjugate molecule comprising D-enantiomeric amino acids in its portion (I). Furthermore, the invention relates to pharmaceutical compositions containing said conjugate molecule as well as to the use of said conjugate molecule for therapeutical treatment. Methods for improving cell permeability are disclosed as well.
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