首页> 外国专利> METHOD AND KIT FOR DETECTING PROLIFERATIVE DISEASES CAUSING SCLEROSIS, PREVENTIVE AND/OR REMEDY FOR PROLIFERATIVE DISEASES CAUSING SCLEROSIS AND METHOD AND KIT FOR IDENTIFYING SUBSTANCE EFFICACIOUS IN PREVENTING AND/OR TREATING PROLIFERATIVE DISEASES CAUSING SCLEROSIS

METHOD AND KIT FOR DETECTING PROLIFERATIVE DISEASES CAUSING SCLEROSIS, PREVENTIVE AND/OR REMEDY FOR PROLIFERATIVE DISEASES CAUSING SCLEROSIS AND METHOD AND KIT FOR IDENTIFYING SUBSTANCE EFFICACIOUS IN PREVENTING AND/OR TREATING PROLIFERATIVE DISEASES CAUSING SCLEROSIS

机译：用于检测由细菌引起的增生性疾病的方法和工具包，用于由细菌引起的增生性疾病的预防和/或补救方法以及用于识别在预防和/或治疗引起细菌性增生的疾病中有效的物质的方法和工具包

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摘要

A method of detecting proliferative diseases causing sclerosis which comprises measuring the expression of at least one substance selected from the group consisting of STAT3, phosphorylated STAT3, Smad1, phosphorylated Smad1, activin receptor-like kinase 1, activin receptor- like kinase 3 and bone morphogenetic protein in a biological sample; a kit therefor; a preventive and/or a remedy for proliferative diseases causing sclerosis which contains, as the active ingredient, a substance having an effect of inhibiting the expression of at least one substance selected from the group consisting of STAT3, phosphorylated STAT3, Smad1 and phosphorylated Smad1; a method of identifying a substance efficacious in preventing and/or treating proliferative diseases causing sclerosis which comprises judging whether or not a test substnace inhibits the expression of at least one substance selected from the group consisting of STAT3, phosphorylated STAT3, Smad1 and phosphorylated Smad1; and a kit therefor. ® KIPO & WIPO 2007

机译：一种检测引起硬化的增生性疾病的方法，该方法包括测量至少一种物质的表达，所述物质选自STAT3，磷酸化STAT3，Smad1，磷酸化Smad1，激活蛋白受体样激酶1，激活蛋白受体样激酶3和骨形态发生生物样品中的蛋白质;相应的工具包;用于引起硬化的增生性疾病的预防和/或治疗，其包含具有抑制至少一种选自STAT3，磷酸化STAT3，Smad1和磷酸化Smad1的物质的表达的物质作为活性成分;一种鉴定对预防和/或治疗引起硬化的增生性疾病有效的物质的方法，该方法包括判断受试物质是否抑制选自STAT3，磷酸化STAT3，Smad1和磷酸化Smad1的至少一种物质的表达;和一个工具包。 ®KIPO和WIPO 2007

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公开/公告号KR20070026303A

专利类型
公开/公告日2007-03-08

原文格式PDF
申请/专利权人 HUBIT GENOMIX INC.;CHUGAI SEIYAKU KABUSHIKIKAISHA;DOI TOSHIO;
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申请/专利号KR20067004858
发明设计人 DOI TOSHIO;ABE HIDEHARU;
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申请日2006-03-09
分类号G01N33/48;G01N33/68;G01N33/53;C12Q1/68;
国家 KR
入库时间 2022-08-21 20:36:28

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