首页> 外国专利> PLANAR SUBSTRATE TYPE PATCH-CLAMP DEVICE FOR MEASURING ION CHANNEL ACTIVITY, SUBSTRATE FOR FABRICATING PATCH-CLAMP DEVICE AND METHOD OF PRODUCING THE SAME

PLANAR SUBSTRATE TYPE PATCH-CLAMP DEVICE FOR MEASURING ION CHANNEL ACTIVITY, SUBSTRATE FOR FABRICATING PATCH-CLAMP DEVICE AND METHOD OF PRODUCING THE SAME

机译：用于测量离子通道活性的平面基板类型的片夹装置，制造基板的片基板及其制造方法

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摘要

A patch-clamp device of the planar substrate type wherein an ultramicropore is formed through a substantially planar SOI substrate, a cell membrane is located around the inlet of the ultramicropore, and electrodes are provided across the cell membrane, the ultramicropore and a conductive liquid so that the current between the electrodes can be taken out. Use of this device makes it possible to measure the activity degree of an ion channel protein in the cell membrane at a high responsiveness.

机译：平面基板类型的膜片钳装置，其中穿过基本平面的SOI基板形成超微孔，细胞膜位于超微孔的入口周围，电极设置在整个细胞膜，超微孔和导电液体之间电极之间的电流可以取出。使用该装置可以以高响应度测量细胞膜中离子通道蛋白的活性程度。

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公开/公告号WO2007116978A1

专利类型
公开/公告日2007-10-18

原文格式PDF
申请/专利权人 INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES;URISU TSUNEO;
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申请/专利号WO2007JP57788
发明设计人 URISU TSUNEO;
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申请日2007-04-06
分类号G01N27/416;G01N27/07;G01N27/28;G01N27/327;C12M1/00;G01N35/08;G01N37/00;
国家 WO
入库时间 2022-08-21 20:46:42

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