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SUBSTRATE FOR PATCH-CLAMP DEVICE, PLANAR SUBSTRATE TYPE PATCH-CLAMP DEVICE, AND METHOD OF MEASURING CELL ION CHANNEL ACTIVITY

机译:膜片钳装置用基板,平面基板型膜片钳装置及细胞离子通道活性的测定方法

摘要

PROBLEM TO BE SOLVED: To provide a planar substrate type patch-clamp device technology which can easily downsize a device and allows simple use, and moreover enables high sensitive and accurate measurement.;SOLUTION: The substrate for the patch-clamp device is an electric insulating substrate in which an aperture on one side in a through-hole connecting both surface sides of the substrate has a bore diameter smaller than that of a cell and an extracellular matrix formative substance is provided on the circumference of the aperture. The planar substrate type patch-clamp device is provided with: liquid reservoirs for holding conductive liquid on the both surface sides of the through-hole of the substrate; and electrodes disposed for energizing the conductive liquid.;COPYRIGHT: (C)2009,JPO&INPIT
机译:要解决的问题:提供一种平面基板型膜片钳设备技术,该技术可以轻松缩小设备尺寸并允许简单使用,并且还可以实现高灵敏度和精确的测量。绝缘基板,其中在连接基板的两个表面侧的通孔中的一侧上的孔的孔径小于电池的孔径,并且在该孔的圆周上设置有细胞外基质形成物质。平面基板型膜片钳装置具有:在基板的贯通孔的两面侧保持导电性液体的储液器;以及在基板的贯通孔的两面侧保持导电性液体的储液器。 ;以及设置用于向导电液体供能的电极。;版权所有:(C)2009,日本特许经营&INPIT

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