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PERFUSION SYSTEM AND APPARATUS FOR AUTOMATED MULTI-CHANNEL PATCH-CLAMP RECORDINGS UTILIZING INSIDE-OUT WHOLE-CELL CONFIGURATION
PERFUSION SYSTEM AND APPARATUS FOR AUTOMATED MULTI-CHANNEL PATCH-CLAMP RECORDINGS UTILIZING INSIDE-OUT WHOLE-CELL CONFIGURATION
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机译:内外全细胞配置的自动多通道斑纹钳位记录的灌注系统和装置
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摘要
A system and method for high throughput patch clamp measurements to study the effect of various chemicals on ion transfer channels is provided. One or more patch clamp configurations is established, each comprising a cell sealed to a pipette. The pipettes are affixed to a pipette fixture. The pipette fixture and a plate comprising one or more wells are relatively moved so that each cell is inside a well. Electrical properties of the cells are measured.
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