首页> 外国专利> Composition comprising of interfering RNA molecules directed against genes related to ocular hypertension, use of said composition for the treatment of ocular hypertensionAnd method to attenuate the expression of a Target mRNA without affecting the expression of a Second Variant mRNA targets of ocular hypertension.

Composition comprising of interfering RNA molecules directed against genes related to ocular hypertension, use of said composition for the treatment of ocular hypertensionAnd method to attenuate the expression of a Target mRNA without affecting the expression of a Second Variant mRNA targets of ocular hypertension.

机译：包含针对与高血压相关基因的干扰RNA分子的组合物，所述组合物在治疗高血压中的用途和减弱靶mRNA表达而不影响高血压的第二变异mRNA靶标表达的方法。

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摘要

Composition attenuates expression of mRNA associated with ocular hypertension and comprising an interfering RNAs of 19 to 49 Nucleotides and a pharmaceutically acceptable Vehicle; use of the compositionFor the treatment of ocular hypertension and Method for reducing the expression of a Target mRNA of ocular hypertension.

机译：组合物减弱与高眼压有关的mRNA的表达，并包含19至49个核苷酸的干扰RNA和药学上可接受的媒介物;该组合物在治疗高眼压症中的用途和减少高眼压靶标mRNA表达的方法。

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公开/公告号CL2006000221A1

专利类型
公开/公告日2007-07-13

原文格式PDF
申请/专利权人 ALCON INC;
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申请/专利号CL2006000221
发明设计人 CHATTERTON JON E.;WAX MARTIN B.;CLARK ABBOT F.;SHEPARD ALLAN R.;
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申请日2006-02-01
分类号A61K48/00;A61P27/02;
国家 CL
入库时间 2022-08-21 20:59:16

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