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Pharmaceutical compositions and Methods comprising a combination of a selective oestrogen Receptor Modulator and an aromatase inhibitor

机译:包含选择性雌激素受体调节剂和芳香酶抑制剂的组合的药物组合物和方法

摘要

1. Pharmaceutical ingredients and treatment methods, including providing a (-) - cis-6-phenyl-5 - [4 - (2-pirrolidin-1-il-etoxi) - phenyl] - 5, 6, 7, 8-tetrahydronaphenyl-2-ol or an acceptable salt or recipe, as well as an aromatic inhibitor to patients in need. In particular, this document deals with pharmaceutical ingredients and treatment methods, including the provision of a combination of (-) - cis-6-phenyl-5 - [4 - (2-pirrolidin-1-il-etoxi) - phenyl] - 5, 6, 7, 8-tetrahydronaphenyl-2-ol or an acceptable salt or hydrochlorofluorocarbon, as well as a specific aromatic inhibitor to patients in need. Carbamate formaldehyde1. Atamistano, anastrazol, fadrozol, finrozol, indiozol, vorozol, 4 - [n - (4-bromobenzene) - N - (4-cyanofluoromethane) amine] - 4h-1, 2, 4-trinitrozole or exemestan, or a salt acceptable for drugs. Item 6: a method for the treatment of senile osteoporosis, postmenopausal osteoporosis, osteoporosis, bone transplantation, breast cancer, ovarian cancer, obesity, osteoporosis, male osteoporosis, vulnerability, muscle injury or scabies, including the management of patients in need,1. Effective amount of (-) - cis-6-phenyl-5 - [4 - (2-pirrolidin-1-il-etoxi) - phenyl] - 5, 6, 7, 8-tetrahydronatelen-2-ol, or acceptable salt or recipe, and effective amount of aromatic inhibitor or acceptable salt or recipe;
机译:1.药物成分和治疗方法,包括提供(-)-顺式-6-苯基-5-[4--(2-吡咯烷-1-il-乙酮)-苯基]-5,6,7,8-四氢萘苯基-2-ol或可接受的盐或配方,以及对有需要的患者的芳香抑制剂。特别是,该文件涉及药物成分和治疗方法,包括提供(-)-cis-6-phenyl-5-[4--(2-pirrolidin-1-il-etoxi)-苯基]-的组合5、6、7、8-四氢萘-2-酚或可接受的盐或氢氯氟烃,以及对需要治疗的患者的特定芳香族抑制剂。氨基甲酸酯甲醛1。 Atamistano,anastrazol,fadrozol,finrozol,indiozol,vorozol,4- [n-(4-溴苯)-N-(4-氰基氟甲烷)胺]-4h-1、2、4-三硝基唑或艾克美斯坦,或可接受的盐毒品。第6项:治疗老年性骨质疏松症,绝经后骨质疏松症,骨质疏松症,骨移植,乳腺癌,卵巢癌,肥胖症,骨质疏松症,男性骨质疏松症,脆弱性,肌肉损伤或sc疮的方法,包括需要治疗的患者的治疗,1。有效量的(-)-顺式-6-苯基-5-[4--(2-吡咯烷-1-il-苯乙酮)-苯基]-5、6、7、8-四氢萘-2-醇或可接受的盐或配方,以及有效量的芳香族抑制剂或可接受的盐或配方;

著录项

  • 公开/公告号AR054258A1

    专利类型

  • 公开/公告日2007-06-13

    原文格式PDF

  • 申请/专利权人 PFIZER PRODUCTS INC.;

    申请/专利号AR2006P101616

  • 发明设计人

    申请日2006-04-24

  • 分类号A61K31/40;A61K31/5685;A61P35/00;A61P21/00;A61P25/02;A61P19/00;A61P15/00;A61P3/04;

  • 国家 AR

  • 入库时间 2022-08-21 20:59:34

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