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BIOCHEMICAL REACTION SYSTEM, BIOCHEMICAL REACTION SUBSTRATE, PROCESS FOR PRODUCING HYBRIDIZATION SUBSTRATE AND HYBRIDIZATION METHOD

机译:生物化学反应系统,生物化学反应物,制备氢化物的方法和杂交方法

摘要

A bioassay substrate (1) is flat and has a disc-shaped main side like an optical disc such as CD. The substrate (1) is rotatable about a central hole (2) formed therein. The substrate (1) has formed on the surface (1a) thereof a plurality of wells (8) where a probe-use DNA (detection-use nucleotide chain) and sample-use DNA (target nucleotide chain) react with each other for hybridization. The substrate (1) has a transparent electrode layer (4) formed as an underlying layer of the well (8). For hybridization, an external electrode (18) is placed in a position near the transparent electrode layer (4) from above the top surface (1a) of the substrate (1) to apply an AC power to between the transparent electrode layer (4) and external electrode (18) in order to apply an AC electric field perpendicularly to the substrate (1).
机译:生物测定用基板(1)是平坦的,具有像CD等的光盘那样的圆盘状的主面。基板(1)可围绕形成在其中的中心孔(2)旋转。基板(1)在其表面(1a)上形成有多个孔(8),在这些孔中探针用DNA(检测用核苷酸链)和样品用DNA(靶核苷酸链)相互反应进行杂交。 。基板(1)具有形成为阱(8)的下层的透明电极层(4)。为了杂交,将外部电极(18)从基板(1)的顶表面(1a)上方置于透明电极层(4)附近的位置,以在透明电极层(4)之间施加交流电。外部电极(18),以便垂直于基板(1)施加交流电场。

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