首页> 外国专利> TREATMENT OF NICOTINE ASSESSMENT AND SEEK CONDITIONAL BEHAVIOR

TREATMENT OF NICOTINE ASSESSMENT AND SEEK CONDITIONAL BEHAVIOR

机译:尼古丁评估和性行为的治疗

摘要

The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method includes administering to a mammal an effective amount of gamma vinylGABA or a pharmaceutically acceptable salt thereof. The present invention also provides a method of treatment of cocaine, morphine, heroin, nicotine, amphetamine, methamphetamine, or ethanol addiction by treating a mammal with an effective amount of gamma vinylGABA or a pharmaceutically acceptable salt thereof. In one embodiment, the method of the present invention includes administering to the mammal an effective amount of a composition which increases central nervous system GABA levels wherein the effective amount is sufficient to diminish, inhibit or eliminate behavior associated with craving or use of drugs of abuse. The composition includes GVG, gabapentin, valproic acid, progabide, gamma-hydroxybutyric acid, fengabine, cetylGABA, topiramate or tiagabine or a pharmaceutically acceptable salt thereof, or an enantiomer or a racemic mixture thereof.
机译:本发明提供了一种用于治疗物质成瘾和改变患有物质成瘾的哺乳动物的成瘾相关行为的高效方法。该方法包括向哺乳动物施用有效量的γ-乙烯基GABA或其药学上可接受的盐。本发明还提供了通过用有效量的γ-乙烯基GABA或其药学上可接受的盐治疗哺乳动物来治疗可卡因,吗啡,海洛因,尼古丁,苯丙胺,甲基苯丙胺或乙醇成瘾的方法。在一个实施方案中,本发明的方法包括向哺乳动物施用有效量的组合物,该组合物增加中枢神经系统GABA水平,其中该有效量足以减少,抑制或消除与渴望或使用滥用药物有关的行为。 。所述组合物包括GVG,加巴喷丁,丙戊酸,普罗布比德,γ-羟基丁酸,丰那滨,十六烷基GABA,托吡酯或替加比滨或其药学上可接受的盐,或对映异构体或其外消旋混合物。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号