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Ribose-substituted aromatic amide antibiotics, active against anaerobic gram positive bacteria such as staphylococci, streptococci, pneumococci, enterococci, and listeria
Ribose-substituted aromatic amide antibiotics, active against anaerobic gram positive bacteria such as staphylococci, streptococci, pneumococci, enterococci, and listeria
Compounds of formula (I); wherein R1=alkyl, alkenyl or alkynyl, O-alkyl, O-alkenyl or optionally substituted, optionally interrupted O-alkynyl; R2=hydrogen or halogen; R3=hydrogen, alkyl or halogen; R4=NHR' or NHOR'', R' or R'' are identical or different and represent hydrogen, alkyl, alkenyl or alkynyl, aryl; R5=hydrogen or O-alkyl; R6=alkyl or CH2-O-alkyl; R7=hydrogen or alkyl or R6 et R7 form a cycle together with the carbon carrying them in addition to the addition salts thereof with bases. The compounds of formula (I) have antibiotic properties.
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机译：式（I）化合物;其中R1 ＝烷基，烯基或炔基，O-烷基，O-烯基或任选取代的，任选间断的O-炔基; R 2 ＝氢或卤素; R 3 ＝氢，烷基或卤素; R4 ＝ NHR′或NHOR″，R′或R″相同或不同，代表氢，烷基，烯基或炔基，芳基; R 5 ＝氢或O-烷基; R6 ＝烷基或CH2-O-烷基; R 7 ＝氢或烷基或R 6和R 7与其一起与碱加成的盐一起与形成碳的环一起形成环。式（I）的化合物具有抗生素特性。
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