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Accentuation of industrial production increasing transport of substrate.

机译:加快工业生产,增加了基材的运输。

摘要

"Accentuation of industrial production and transport of the substrate.Method for increasing production biossintu00e9tica host cell of a desired compound derived from at least one way partially intracellular said host cell is described.Such a method includes selecting a host cell that has at least one way which uses a partially synthetic intracellular extracellular substrate; increase the transport of said substrAct in such extracellular host cell while maintaining the integrity of the host cell.Cultivating the host cell to produce the said extracellular substrate; and to produce the desired compound.The transport of the substrate is increased by transforming the host cell DNA encoding one or more enzymes carrying the substrate in the host cell.
机译:着重于工业生产和底物的运输。描述了用于增加所需化合物的生物生产的方法,所述所需化合物衍生自至少部分地在所述细胞内的所述宿主细胞。这种方法包括选择具有至少至少一种使用部分合成的细胞内胞外底物的方法;增加所述substrAct在此类细胞外宿主细胞中的运输,同时保持宿主细胞的完整性。培养所述宿主细胞以产生所述胞外底物;并产生所需化合物。通过转化宿主细胞中编码一种或多种在宿主细胞中携带底物的酶的DNA来增加底物的运输。

著录项

  • 公开/公告号BR0113032A

    专利类型

  • 公开/公告日2006-02-21

    原文格式PDF

  • 申请/专利权人 GENENCOR INTERNATIONAL INC;

    申请/专利号BR20010113032

  • 发明设计人 FERNANDO VALLE;MANOJ KUMAR;

    申请日2001-08-03

  • 分类号C12N15/31;C07K14/24;C12N1/21;C12P1/00;C12P7/60;

  • 国家 BR

  • 入库时间 2022-08-21 21:40:22

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