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Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof
Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof
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机译：能够释放两个或多个一氧化氮分子的噻唑类一氧化氮供体及其用途
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摘要
Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.
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