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The immunization mannered null nonpoisonous conversion swine erysipelas germ YS1 stocks by the swine erysipelas germ and the said
The immunization mannered null nonpoisonous conversion swine erysipelas germ YS1 stocks by the swine erysipelas germ and the said
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机译:通过猪丹毒菌种的疫苗免疫无效的无毒转化猪丹毒菌种YS1,
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摘要
PROBLEM TO BE SOLVED: To solve a problem that diseases such as Erysipelothrix rhusiopathiae, Mycoplasma hyopneumoniae, etc., exist in a pig farming industry, various kinds of vaccines are required to healthily breed pigs, however, stress is imposed on pigs by a vaccine injection itself so that in order to alleviate the stress, development of a vaccine capable of decreasing the number of times of vaccine injections and immunizing pigs against several kinds of diseases by one vaccine injection is desired.;SOLUTION: This swine Erysipelothrix rhusiopathiae YS-19 strain expresses a part of P97 adhesin being an adhesive protein on the surface of a microbial cell of detoxicated swine Erysipelothrix rhusiopathiae. This method for immunization comprises preparing a protein and a gene cassette and administering a microbial cell of the YS-19 strain to an animal. This method for immunization comprises preparing a gene cassette from which a part of a gene encoding a surface antigen of swine Erysipelothrix rhusiopathiae and to which a part of P97 adhesin gene of the Mycoplasma hyopneumoniae is inserted, a protein and swine Erysipelothrix rhusiopathiae and administering the protein to an animal.;COPYRIGHT: (C)2002,JPO
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