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METHOD FOR BREAST CANCER PROGNOSTICS BY IDENTIFYING DIFFERENTIAL MODULATION OF EACH GENE RELATIVE TO THE EXPRESSION OF THE SAME GENES IN NORMAL POPULATE
METHOD FOR BREAST CANCER PROGNOSTICS BY IDENTIFYING DIFFERENTIAL MODULATION OF EACH GENE RELATIVE TO THE EXPRESSION OF THE SAME GENES IN NORMAL POPULATE
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机译：通过识别相对于正常人群中相同基因表达的每种基因的差异调节来确定乳腺癌预后的方法
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摘要
PURPOSE: A method for breast cancer prognostics is provided, thereby accurately prognosing whether the breast cancer is relapsed or metastasized in a patient diagnosed with or treated for breast cancer. CONSTITUTION: The method for breast cancer prognostics comprises identifying differential modulation of each gene relative to the expression of the same genes in a normal populate in a combination of genes having the nucleotide sequences selected from SEQ ID NO:1 to SEQ ID NO:56, wherein the expression of the modulated genes has difference of 2 fold or more; the genes selected are up-regulated as a mark of relapse or metastasis; the genes selected are down-regulated as a mark of relapse or metastasis; and the p value showing the differential modulation is 0.05 or less.
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机译：目的：提供一种用于乳腺癌预后的方法，从而准确地诊断或诊断患有乳腺癌的患者是否复发或转移了乳腺癌。组成：乳腺癌的预后方法包括：鉴定每个基因相对于正常人群中相同基因的表达的差异调节，该组合的核苷酸序列选自SEQ ID NO：1至SEQ ID NO：56，其中调节基因的表达具有2倍或更大的差异;选择的基因被上调，作为复发或转移的标志;选择的基因被下调，作为复发或转移的标志;表示微分调制的p值为0.05以下。
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