首页> 外国专利> OLIGO AND POLYSACCHARIDES FOR HEMOSPATIBLE COATING, METHOD FOR THEIR RECEIVING, COATED MEDICAL DEVICE (OPTIONS) AND METHOD FOR DRAWING A HEMOSPATIBLE COVERING ON MEDICAL TYPE

OLIGO AND POLYSACCHARIDES FOR HEMOSPATIBLE COATING, METHOD FOR THEIR RECEIVING, COATED MEDICAL DEVICE (OPTIONS) AND METHOD FOR DRAWING A HEMOSPATIBLE COVERING ON MEDICAL TYPE

机译:用于难溶性涂层的寡糖和多糖,其接收方法,带涂层的医疗器械(选件)以及在医疗类型上绘制难溶性覆盖物的方法

摘要

The invention relates to oligosaccharides and polysaccharides, as well as to the use of oligosaccharides and / or polysaccharides that contain the sugar unit N-acylglucosamine or N-atsilgalaktozamina to obtain hemocompatible surfaces, and to methods of applying on the surface of the hemocompatible coating with data oligosaccharides and and / or polysaccharides that mimic the substance of the usual biosynthetic precursor heparin, heparan sulfates and chitosan. In addition, the invention describes methods for producing these oligosaccharides and / or polysaccharides and discloses various possibilities for using surfaces with a hemocompatible coating. In particular, the invention relates to the use of said oligosaccharides and / or polysaccharides on stents with at least one hemocompatible coating applied according to the invention, which contains an antiproliferative, anti-inflammatory and / or antithrombotic active agent, methods of making these stents, as well as the use of these stents for warnings restenosis. The international application was published along with an international search report.
机译:本发明涉及寡糖和多糖,以及含有糖单元N-酰基葡糖胺或N-atsilgalaktozamina的寡糖和/或多糖在获得血液相容性表面中的用途,并涉及在具有血数据模拟了通常的生物合成前体肝素,硫酸乙酰肝素和壳聚糖的物质的寡糖和/或多糖。另外,本发明描述了用于生产这些寡糖和/或多糖的方法,并公开了使用具有血液相容性涂层的表面的各种可能性。特别地,本发明涉及所述寡糖和/或多糖在具有至少一种根据本发明施加的血液相容性涂层的支架上的用途,所述涂层包含抗增殖,抗炎和/或抗血栓形成活性剂,制造这些支架的方法,以及将这些支架用于警告再狭窄。国际申请与国际检索报告一同发布。

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