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首页> 外国专利> A compound or a pharmaceutically acceptable form thereof, pharmaceutical composition, methods of reducing calcium conductance of a cellular capsaicin receptor, and inhibiting vanilloid ligand binding to a capsaicin receptor, methods of treating a condition responsive to capsaicin receptor modulation. , pain, itching, coughing or hiccups, urinary incontinence, promoting weight loss in a patient, and determining the presence or absence of capsaicin receptor in a sample, packaged pharmaceutical preparation, and use of a compound

A compound or a pharmaceutically acceptable form thereof, pharmaceutical composition, methods of reducing calcium conductance of a cellular capsaicin receptor, and inhibiting vanilloid ligand binding to a capsaicin receptor, methods of treating a condition responsive to capsaicin receptor modulation. , pain, itching, coughing or hiccups, urinary incontinence, promoting weight loss in a patient, and determining the presence or absence of capsaicin receptor in a sample, packaged pharmaceutical preparation, and use of a compound

机译：化合物或其药学上可接受的形式，药物组合物，降低细胞辣椒素受体的钙电导率和抑制类辣椒素配体与辣椒素受体结合的方法，治疗对辣椒素受体调节有响应的病症的方法。 ，疼痛，瘙痒，咳嗽或打ic，尿失禁，促进患者体重减轻以及确定样品，包装的药物制剂中辣椒素受体的存在与否以及化合物的用途

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"COMPOUND OR PHARMACEUTICALLY ACCEPTABLE FORM OF THE SAME, PHARMACEUTICAL COMPOSITION, METHODS OF REDUCING CALCIUM CONDUCTANCE RECEIVER, AND INHIBIT CONNECTION OF THE RECYPTUS CABLE RECEPTOR CABLE CONDUCTION CAPSAICIN, PAIN, ITCHING, CUSHING OR SOLUTIONS, URINARY INCONTINENCE, TO PROMOTE LOSS OF WEIGHT IN A PATIENT, AND TO DETERMINE THE PRESENCE OR ABSENCE OF CAPSAICINE RECEIVER IN A SAMPLE, PREPARATION, PHARMACEUTICAL, "PHARMACEUTICAL," PREPARATION Certain 2-substituted quinazolin-4-ylamine analogs are provided. Such compounds are ligands that can be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in treating conditions associated with pathological receptor activation. in humans, domesticated pets and farm animals. Pharmaceutical compositions and methods for using them in the treatment of said disorders are provided, as well as methods for using said binders for receptor localization studies.
机译：“化合物或药物可接受的同一种形式，药物成分，减少钙电导接收器的方法，以及禁止将RECEPTAS电缆接收器电缆的导线电容，疼痛，结点，插入，插入或插入连接病人，以及确定样品中是否存在辣椒素受体的方法，制备方法，药物，“药物”的制备方法提供了某些2-取代的喹唑啉-4-基胺类似物，这类化合物是可用于调节特定受体的配体在体内或体外具有活性，并特别用于治疗人，家养宠物和农场动物中与病理性受体活化有关的疾病，提供了用于治疗所述疾病的药物组合物和方法，以及用于治疗所述疾病的方法。使用所述粘合剂进行受体定位研究。

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