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Methods for identifying, viewing, and analyzing syntenic and orthologous genomic regions between two or more species

机译:识别,查看和分析两个或多个物种之间的同系和直系基因组区域的方法

摘要

A method and interactive screen system for identifying orthologous genomic regions between two or more species can be provided. The method can involve performing a BLAST search using each of the two or more species against each of the other of the two or more species and identifying the best ortholog matches. The interactive screen system can display one or more of (a) a map viewer which can show genomic sequence information of the two or more species with markers therein, (b) a TA viewer which can show at least one contig and fragments which generated the contig, (c) an evidence viewer which can anotate transcribed regions of the genomic data, (d) a synteny viewer which can show syntenic relationships between the genomic sequence data, (e) a multiple sequence alignment viewer which can show multiple sequence alignments of genomic sequences, and (f) a trace viewer which can show single nucleotides in genomic sequences.
机译:可以提供一种用于识别两个或多个物种之间的直系同源基因组区域的方法和交互式屏幕系统。该方法可以包括使用两个或更多个物种中的每个相对于两个或更多个物种中的另一个来执行BLAST搜索,并识别最佳直向同源物匹配。交互式屏幕系统可以显示以下一种或多种:(a)地图查看器,可以显示两个或多个物种的基因组序列信息,其中有标记;(b)TA查看器,可以显示至少一个重叠群和产生该序列的片段contig,(c)可以注释基因组数据转录区域的证据查看器,(d)可以显示基因组序列数据之间同位关系的Synteny查看器,(e)可以显示以下序列的多个序列比对的多序列比对查看器基因组序列;和(f)示踪剂,可显示基因组序列中的单个核苷酸。

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