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DISEASE MODEL MOUSE OF SPONTANEOUS RHEUMARTHRITIS AND SCREENING METHOD FOR PROPHYLACTIC/THERAPEUTIC AGENT FOR RHEUMARTHRITIS USING THE MODEL MOUSE
DISEASE MODEL MOUSE OF SPONTANEOUS RHEUMARTHRITIS AND SCREENING METHOD FOR PROPHYLACTIC/THERAPEUTIC AGENT FOR RHEUMARTHRITIS USING THE MODEL MOUSE
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机译:自发性风湿关节炎的疾病模型小鼠和使用该模型小鼠的风湿性关节炎的预防/治疗剂筛选方法
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摘要
PROBLEM TO BE SOLVED: To provide a disease model mouse of spontaneous rheumarthritis that can be widely and repeatedly used as an experimental study material for articular rigidity/deformation and functional disorder caused by rheumarthritis and for investigating the causing mechanism, prevention, diagnosis, therapy and the like of articular rigidity/deformation and functional disorder.;SOLUTION: The newly created disease model mouse of spontaneous rheumarthritis according to this invention has a character that spontaneously develops rheumarthritis and the character originates from F1 BXB-khs male mouse having an H-2 heterozygote from an ancestry BXSB female mouse and an NZB male mouse.;COPYRIGHT: (C)2006,JPO&NCIPI
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