首页> 外国专利> DIAGNOSTIC AND THERAPEUTIC USE OF THE ARGININE VASOPRESSIN RECEPTOR 2 (AVPR2)

DIAGNOSTIC AND THERAPEUTIC USE OF THE ARGININE VASOPRESSIN RECEPTOR 2 (AVPR2)

机译:精氨酸血管加压素受体2(AVPR2)的诊断和治疗用途

摘要

The invention provides a human AVPR2 which is associated with the hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, genitourinary diseases, respiratory diseases, metabolic diseases and cancer. The invention also provides assays for the identification of compounds useful in the treatment or prevention of hematological diseases, cardiovascular diseases, disorders of the peripheral and central nervous system, genitourinary diseases, respiratory diseases, metabolic diseases and cancer. The invention also features compounds which bind to and/or activate or inhibit the activity of AVPR2 as well as pharmaceutical compositions comprising such compounds.
机译:本发明提供了人AVPR2,其与血液疾病,心血管疾病,周围和中枢神经系统疾病,泌尿生殖系统疾病,呼吸系统疾病,代谢疾病和癌症有关。本发明还提供了用于鉴定可用于治疗或预防血液疾病,心血管疾病,周围和中枢神经系统疾病,泌尿生殖系统疾病,呼吸系统疾病,代谢疾病和癌症的化合物的测定法。本发明的特征还在于结合和/或激活或抑制AVPR2活性的化合物,以及包含此类化合物的药物组合物。

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