首页>
外国专利>
REGULATION OF TRANSCRIPTION ELONGATION FACTORS
REGULATION OF TRANSCRIPTION ELONGATION FACTORS
展开▼
机译:转录延伸因子的调节
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to agents, including siRNA and shRNA molecules, small molecules, antisense strands, and ribozymes that are targeted to transcription elongation factors (TEFs), including CDK9 and CycTI, subunits of P-TEFb, Spt4 and Spt5, subunits of DSIF (DRB Sensitivity-Inducing Factor (DSIF)), and Spt6. The present invention also relates to methods for treating disorders associated with aberrant or unwanted TEF expression or activity, including HIV and disorders characterized by unwanted or aberrant cellular proliferation or differentiation, such as cancer.
展开▼