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INHIBITING 6-AZAURALIC DERIVATIVES OF IL-5.
INHIBITING 6-AZAURALIC DERIVATIVES OF IL-5.
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机译：抑制IL-5的6-天金衍生物。
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摘要
A compound of formula ** formula ** an N-oxide, a pharmaceutically acceptable addition salt or a stereochemically isomeric form thereof, in which: p represents an integer that is 0, 1, 2 or 3; q represents an integer that is 0, 1, 2, 3 or 4; -A-B- represents ¿(CH2) r-, - (CH2) t-O-, - (CH2) t-S (= O) u- or ¿(CH2) t-NR3-; r represents 2, 3 or 4; each t independently represents 1, 2 or 3; u represents 0, 1 or 2; X1 represents O, S, NR3 or a direct link; each R1 independently represents C1-6 alkyl, halo, polyhalo-C1-6 alkyl, hydroxy, mercapto, C1-6 alkyloxy, C1-6 alkylthio, C1-6 alkylcarbonyloxy, aryl, cyano, nitro, Het3, R6, NR7R8 or alkyl C1-4 substituted with Het3, R6 or NR7R8; each R4 independently represents C1-6 alkyl, halo, polyhalo-C1-6 alkyl, hydroxy, mercapto, C1-6 alkyloxy, C1-6 alkylthio, C1-6 alkylcarbonyloxy, aryl, cyano, nitro, Het3, R6, NR7R8 or alkyl C1-4 substituted with Het3, R6 or NR7R8.
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