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Decision manner null of the liver cell cancer which uses the marker and the said marker for liver cell cancer decision
Decision manner null of the liver cell cancer which uses the marker and the said marker for liver cell cancer decision
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机译:使用标记物和所述标记物进行肝细胞癌判定的肝细胞癌判定方式无效
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摘要
PURPOSE: To judge the danger of the advance and of the outbreak of hepatoma by using a marker, for judgement of hepatoma, which uses a seventh GIa incomplete blood coagulation factor (PIVKA-VII) as essence. ;CONSTITUTION: A monoclonal antibody which does not react with a seventh blood coagulation factor but which has a reactivity only to a PIVKA-VII is prepared, it is used as a solid-phase antibody or a marker antibody in an enzyme immunoassay method or a radioimmunoassary method based of a double antibody sandwich assay method, and the PIVKA-VII in a biological sample is detected directly. The existence of the PIVKA-VII indicates a positive rate of 100% at patients who are positive to α1 fetoprotein (AFP) and who are positive to the PIVKA-VII, and it displays a positive rate of 100% even at patients who are negative to the AFP but who are positive to the PIVKA-VII. In addition, since 83% of patients who are negative to both AFP and PIVKA-VII markers, are positive, a hepatoma patient can be screened at an extremely high probability.;COPYRIGHT: (C)1996,JPO
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