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A method for the production of surface coatings, the adsorption of proteins and / or the adhesion of bacteria and / or cells reduce

机译:一种生产表面涂层,减少蛋白质吸附和/或减少细菌和/或细胞粘附的方法

摘要

In the case of a method for the production of surface coatings, the adsorption of proteins and / or the adhesion of bacteria and / or cells is reduced, wherein at least parts of the object are provided with a functionalized polymer layer, it is proposed that for the preparation of the polymer layer from the starting compounds of the general structure (1) at temperatures between 500 and 1000 deg c and reduced pressures of less than 500 pa in the substantially monomers in the gas phase, and to produce these are then converted by cooling to polymerize at a reduced temperature, comprising: dollar f1 r φ n φ (n = 1, 2, 3, 4): hydrogen, alkyl, aryl groups, ether, ethylene glycol, cyclic ethers, krohnenether, primary amides, secondary amides, ethylene glycol containing primary amides, ethylene glycol which is contained in the secondary amides, urethanes, ethylene glycol contained urethanes, carbamates, ethylene glycol which is contained in the carbamates, lactam, imines, hydrazones, esters, ethylene glycol containing esters, anhydrides, nitro compounds, amines, thiols, ch φ 2 φ ome, ch φ 2 φ ococh.sub.3 φ 3 φ, ch φ 2 φ ococf φ 3 φ, φ 3 cocf φ, φ φ 2 ch oh, (ch φ 2 φ oh) φ 2 φ, bromide, iodide, chloride, lactone, nitrile, penta fluorine phenol esters, triflate. Dollars a the entire, or else only a part of this functionalized polymer layer can per se protein - and / or cell, or alternatively, end in a further step with an immobilizing coating are provided, i.e, with a layer of immobilized molecules, the protein - and / or cell skilled in the end properties ..
机译:在生产表面涂层的方法的情况下,减少了蛋白质的吸附和/或细菌和/或细胞的粘附,其中至少物体的一部分设有官能化的聚合物层。用于在500至1000℃之间的温度和小于500pa的减压下在气相中的基本单体中由通式(1)的起始化合物制备聚合物层,然后将其转化为通过冷却以在降低的温度下聚合,包括:美元f1 rφnφ(n = 1,2,3,4):氢,烷基,芳基,醚,乙二醇,环醚,k烯醚,伯酰胺,仲酰胺,包含伯酰胺的乙二醇,包含在仲酰胺中的乙二醇,氨基甲酸酯,包含乙二醇的氨基甲酸酯,氨基甲酸酯,包含在氨基甲酸酯中的乙二醇,内酰胺,亚胺,,酯,e包含酯,酸酐,硝基化合物,胺,硫醇的乙二醇,chφ2φome,chφ2φ约3φ3φ,chφ2φococfφ3φ,φ3 cocfφ,φφ2 CH OH,(CHφ2φOH)φ2φ,溴化物,碘化物,氯化物,内酯,腈,五氟酚酯,三氟甲磺酸盐。该功能化聚合物层的整个本身或仅一部分可以本身是蛋白质和/或细胞的美元,或者可替代地,在另一步骤中提供具有固定涂层的末端,即具有固定化分子的层,蛋白质和/或细胞的最终性质熟练。

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