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A new antitumor agent comprising by effective element biscarboxyethylgermanium sesquioxide-transition metal complexes and derivatives thereof
A new antitumor agent comprising by effective element biscarboxyethylgermanium sesquioxide-transition metal complexes and derivatives thereof
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机译:一种新的抗肿瘤剂,包括有效成分的双羧乙基锗倍半氧化物-过渡金属配合物及其衍生物
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摘要
PURPOSE: Provided are biscarboxyethylgermanium sesquioxide-transition metal complexes and their derivatives which have less toxicity but excellent anticancer effects on a human body. And a new antitumor agent comprising them as an effective ingredient is also provided. CONSTITUTION: Biscarboxyethylgermanium sesquioxide-transition metal complex is represented by the formula(1), in which R is hydrogen atom or -NH-R1, wherein R1 is selected from radicals described in the description; and M is divalent transition metal selected from Zn, Hg, Cd, Ni, Mn, Cu and Fe, or monovalent transition metal, Ag, when M is Ag, a complex is represented by the formula(1a).
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