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- A new antitumor agent comprising by effective element biscarboxyethylgermanium sesquioxide-transition metal complexes and derivatives thereof

机译:-一种新型抗肿瘤剂,其包含有效成分的双羧乙基锗倍半氧化物-过渡金属配合物及其衍生物

摘要

PURPOSE: Provided are biscarboxyethylgermanium sesquioxide-transition metal complexes and their derivatives which have less toxicity but excellent anticancer effects on a human body. And a new antitumor agent comprising them as an effective ingredient is also provided. CONSTITUTION: Biscarboxyethylgermanium sesquioxide-transition metal complex is represented by the formula(1), in which R is hydrogen atom or -NH-R1, wherein R1 is selected from radicals described in the description; and M is divalent transition metal selected from Zn, Hg, Cd, Ni, Mn, Cu and Fe, or monovalent transition metal, Ag, when M is Ag, a complex is represented by the formula(1a).
机译:用途:提供了双羧乙基锗倍半氧化物过渡金属配合物及其衍生物,它们的毒性较小,但对人体具有优异的抗癌作用。并且还提供了包含它们作为有效成分的新的抗肿瘤剂。组成:双羧乙基锗倍半氧化物-过渡金属配合物由式(1)表示,其中R为氢原子或-NH-R1,其中R1选自说明书中所述的基团; M为选自Zn,Hg,Cd,Ni,Mn,Cu和Fe中的二价过渡金属或一价过渡金属Ag,当M为Ag时,配合物由式(1a)表示。

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