首页> 外国专利> TOPICAL SOLUTIONS FOR THE TREATMENT OF NASAL SYMPTOMS IN THE COMMON COLD FOR NEWBORN INFANTS, CHILDREN AND ADULTS

TOPICAL SOLUTIONS FOR THE TREATMENT OF NASAL SYMPTOMS IN THE COMMON COLD FOR NEWBORN INFANTS, CHILDREN AND ADULTS

机译:新生儿,婴儿和成人共同感冒中鼻部症状的典型治疗方法

摘要

Common cold is a viral infection resulting predominantly in inflammation ofthe nasalmucosa. The most prevalent symptoms are nasal congestion (resulting inobstruction),and nasal discharge.The solutions proposed are intended for topical intranasal use in newborn,infants, youngand older children, and adults. The main ingredients concentration will varyaccording tothe patient's age, effects and side effects observed during the studies.The main ingredient of these solutions is the steroid, Bethamethasone orDexamethasone.These can be used alone or in combination with an Aminoglycoside antibiotic(Tobramycin or Gentamycin) and/or an anticholinergic agent, such as Ipatropiumbromide.The steroid will act as an anti-inflammatory agent and as such, will relievenasal edema,congestion and obstruction. The anticholinergic agent will decrease nasaldischargethrough the parasympathetic nervous system. The antibiotic used may act on thenasalbacterial flora and its interaction with an infected, damaged nasal mucosa.
机译:普通感冒是一种病毒感染,主要导致鼻黏膜。最普遍的症状是鼻充血(导致梗阻),和鼻涕。提出的解决方案旨在用于新生儿的鼻内局部使用,婴幼儿以及年龄较大的儿童和成人。主要成分浓度会有所不同根据研究期间观察到的患者年龄,影响和副作用。这些溶液的主要成分是类固醇,倍他米松或地塞米松。这些可单独使用或与氨基糖苷类抗生素结合使用(妥布霉素或庆大霉素)和/或抗胆碱能药,例如异丙托溴铵溴化物。类固醇将作为一种抗炎药,因此可以缓解鼻水肿充血和阻塞。抗胆碱药会减少鼻腔卸货通过副交感神经系统。使用的抗生素可能会作用于鼻细菌菌群及其与感染的受损鼻粘膜的相互作用。

著录项

  • 公开/公告号CA2361345A1

    专利类型

  • 公开/公告日2003-04-19

    原文格式PDF

  • 申请/专利权人 LEVY MAURICE;

    申请/专利号CA20012361345

  • 发明设计人 LEVY MAURICE;

    申请日2001-10-19

  • 分类号A61K31/573;A61P31/12;A61P27/14;

  • 国家 CA

  • 入库时间 2022-08-21 23:58:40

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