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Atmospheric pressure ionization ion mobility spectrometry

机译:大气压电离离子迁移谱

摘要

A high voltage ion propulsion field is applied across the length of an ion mobility spectrometer that is divided by a barrier wall into a desolvation region and a drift tube. A plume of ions and solvent is electrosprayed into the desolvation region, and ions are propelled from the desolvation region through the drift tube to an ion target. Drift gas flows through the drift tube in the opposite direction to oppose the ion flow. A portal in the barrier wall permits ions to move from the desolvation region into the drift tube, and restricts flow of drift gas from the drift tube into the desolvation region. The resulting drift gas velocity increase effects desolvation without requiring elevated temperature or decreased pressure. An ion gate is located near the portal and an aperture grid is located near the ion target. The drift gas flow rate is varied to change the ionization spectra to alter selectivity.
机译:跨离子迁移谱仪的整个长度施加高电压离子推进场,该离子迁移谱仪被势垒壁划分为去溶剂化区域和漂移管。将一束离子和溶剂电喷入去溶剂化区域,然后将离子从去溶剂化区域通过漂移管推进到离子靶。漂移气体以相反的方向流过漂移管,以与离子流相反。阻挡壁中的入口允许离子从去溶剂化区域移动到漂移管中,并限制漂移气体从漂移管进入去溶剂化区域的流动。所产生的漂移气体速度增加实现了去溶剂化,而无需升高温度或降低压力。离子门位于入口附近,孔栅位于离子靶附近。改变漂移气体的流速以改变电离光谱以改变选择性。

著录项

  • 公开/公告号US6586732B2

    专利类型

  • 公开/公告日2003-07-01

    原文格式PDF

  • 申请/专利权人 BRIGHAM YOUNG UNIVERSITY;

    申请/专利号US20010788837

  • 发明设计人 MILTON L. LEE;DAVID C. COLLINS;

    申请日2001-02-20

  • 分类号H01J490/00;H01J494/00;B01D594/40;

  • 国家 US

  • 入库时间 2022-08-22 00:05:40

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