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Nucleic acid sequences of CIITA genes which can be involved in controlling and regulating the expression of genes encoding MHC type II molecules, and their use, in particular as drugs
Nucleic acid sequences of CIITA genes which can be involved in controlling and regulating the expression of genes encoding MHC type II molecules, and their use, in particular as drugs
The present invention relates to nucleic acid sequences which comprise all or part of a nucleic acid sequence of a CIITA gene. These sequences can comprise a sequence which exhibits a transcriptional promoter activity, which activity is, in particular, specifically expressed in one cell type. The sequences can also comprise a coding sequence.;Therapeutic and diagnostic applications, in particular relating to disorders in which it is desirable to act on the level at which genes which encode the class II molecules of the major histocompatibility complex (MHC) are expressed.
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