Method for increasing gamma-aminobutyric acid content in rice young leaves

• 1. 一种增加茶叶中r-氨基丁酸含量提升茶叶质量的方法 [P] . 中国专利： CN105475523A . 2016-04-13
• 2. 一种增加茶叶中γ－氨基丁酸含量的方法 [P] . 中国专利： CN1141026C . 2004.03.10
• 3. METHOD FOR INCREASING gamma-AMINOBUTYRIC ACID CONTENT OF RICE YOUNG LEAF [P] . 日本专利： JP2002058445A . 2002-02-26

  机译： 增加小米叶片γ-氨基丁酸含量的方法

• 4. METHOD FOR INCREASING CONTENT OF GAMMA-AMINOBUTYRIC ACID OF GINGKO LEAVES, THEREBY IMPROVING CRANIAL BLOOD FLOW, BRAIN METABOLISM, BLOOD CIRCULATION AND BRAIN DYSFUNCTION [P] . 韩国专利： KR20040100415A . 2004-12-02

  机译： 增加银杏叶γ-氨基丁酸含量，改善颅内血流，脑代谢​​，血液循环和脑功能障碍的方法

• 5. INCREASE IN gamma-AMINOBUTYRIC ACID CONTENT IN BARLEY OR WHEAT YOUNG LEAF [P] . 日本专利： JP2001029041A . 2001-02-06

  机译： 大麦或小麦幼叶中γ-氨基丁酸含量的增加

• 1. Effects of Exogenous Amino Acids on the Contents of Amino Acids in Tobacco Leaves [J] . WU Xue-ping, LIU Guo-shun, ZHU Kai, 农业科学学报（英文版） . 2005,第002期
• 2. Identification of Gamma-Aminobutyric Acid (GABA) and Dietary Fiber of Indonesian Local Germinated Brown Rice (GBR) [C] . Ilzamha Hadijah Rusdan, Gusti Ayuning Kukilo, Sonny Witanto International Conference on Bioinformatics and Nanomedicine from Natural Resources for Biomedical Research . 2019
• 3. High performance liquid chromatographic method to determine natural folate (5-methyltetrahydrofolate) and added folic acid content in food matrices. [D] . Musukula, Sudheer Reddy. 2005
• 4. Antisense Inhibition of Rubisco Activase Increases Rubisco Content and Alters the Proportion of Rubisco Activase in Stroma and Thylakoids in Chloroplasts of Rice Leaves [O] . SONG-HENG JIN, JIAN HONG, XUE-QIN LI, 2006
• 5. Figure 4: The effect of increasing doses of NaCl on the chemical composition of leaves (n = 8) of A. platanoides and A. campestre in the pot experiment: (A) Cl content, (B) Na content, (C) polyprenol content, and (D) ratio of organic acids to the sum of anions. Different letters indicate significant differences between the doses and species (P < 0.05). [O] . -1

• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. Reduced nitrogen availability during growth improves quality in red oak lettuce leaves by minimizing nitrate content, and increasing antioxidant capacity and leaf mineral content [J] . Dario Stefanelli ,Sonja Winkler ,Rod Jones . 农业科学（英文） . 2011,第4期
• 3. iIn Vivo/iSedative and Anxiolytic Activities of iThunbergia erecta/i(Acanthaceae) Leaves Activate Gamma-Aminobutyric Acid (GABA) Mediated Hyperpolarization in Swiss Albino Mice [J] . Anawara Begum ,Abul Hossen ,Ayasha Akter Moly . 药理与制药（英文） . 2019,第4期
• 4. Aluminum Contents in Dry Leaves and Infusions of Commercial Black and Green Tea Leaves: Effects of Sucrose and Ascorbic Acid Added to Infusions [J] . Diego Armando Bárcena-Padilla ,Marisela Bernal-González ,Amalia Panizza-de-León . 自然资源（英文） . 2011,第3期
• 5. 浸泡处理对茶叶中γ-氨基丁酸含量的影响研究 [C] . 郑红发 ,黄怀生 ,黄亚辉 . 第三届海峡两岸茶业博览会暨茶业国际高峰论坛 . 2009
• 6. 家蚕中谷丙转氨酶活力及桑叶中荞麦碱、γ-氨基丁酸含量的快速直接质谱分析 [A] . 李无双 . 2018