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transgenic rats in their genome at least one human gene, which is involved in the blutdruckregulation

机译:转基因大鼠的基因组中至少有一个人类基因,该基因参与了鸭嘴调控

摘要

The invention relates to transgenic rats in whose genome at least one human gene whose gene product is involved in the regulation of blood pressure is integrated. The invention further relates to transgenic rats and their progeny which have an elevated blood pressure (90/140 mm Hg) or high blood pressure (95/160 mm Hg). Finally, the invention relates to processes for the production of the transgenic rats according to the invention and their progeny and to the use thereof for pharmacological investigations.
机译:本发明涉及转基因大鼠,在其基因组中整合了至少一个其基因产物参与血压调节的人类基因。本发明进一步涉及具有升高的血压(> 90 />至140mm Hg)或高血压(> 95 />至160mmHg)的转基因大鼠及其后代。最后,本发明涉及生产根据本发明的转基因大鼠及其后代的方法,并涉及其在药理学研究中的用途。

著录项

  • 公开/公告号DE59209954D1

    专利类型

  • 公开/公告日2002-06-06

    原文格式PDF

  • 申请/专利权人 GANTEN DETLEV;

    申请/专利号DE19925009954T

  • 申请日1992-08-13

  • 分类号C12N15/00;

  • 国家 DE

  • 入库时间 2022-08-22 00:26:03

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